Virus validation data

Virus validation data

Virus I (Influenza Virus)  Solution ClO2（1ppm）

Methods: Solutions of various substances （each at a concentration of 1 ppm） were allowed to work upon Virus I , and the virus infectivity titer was measured. Results: Results suggest that 1 ppm chlorine dioxide suppressed virus infectivity at least 100-fold compared to 1 ppm sodium hypochlorite. No suppression of infectivity titer was observed for 1 ppm sodium chlorite （commonly known as stabilized chlorine dioxide）.

Virus I (Influenza Virus) Method: Mortality rates among 10 mice were compared over 21 days when exposed to either chlorine dioxide gas （0.03 ppm） or air for 15 minutes simultaneously with Virus I （1LD50）

Results-1:

In the presence of 0.03 ppm chlorine dioxide gas, the death of mice due to infection with Virus I was prevented （p ＝ 0.002）. The level of chlorine dioxide gas to which humans can safely be exposed for long periods of time is 0.1 ppm （time-weighted average [TWA] for human exposure for 8 hours.

Results-2: In the presence of chlorine dioxide gas （0.03 ppm）, Virus I in the lungs of mice was significantly reduced（p = 0.003）

Virus N (Norovirus)
Method: Solutions with various substances were allowed to work upon Virus N, and the virus infectivity titer
was measured.
Results: Results suggest that 4 ppm chlorine dioxide suppressed the virus infectivity at least 100-fold
compared to 4 ppm sodium hypochlorite. No suppression of infectivity titer was observed for sodium chlorite （commonly known as stabilized chlorine dioxide） even at 100 ppm. Solution ClO2（1ppm）

Source:https://www.seirogan.co.jp/en/research_dev/eiseidata.html#ancher1